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Sundarrajan, T.
- Hypolipidemic Activity of Amaranthus Tristis Linn in Triton WR-1339 Induced Hyperlipidemic Rats
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Affiliations
1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, IN
2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, IN
1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, IN
2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 1 (2017), Pagination: 171-173Abstract
Hyperlipidemia is the greatest risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Herbal treatment for hyperlipidemia has no side effects and is relatively low cost and locally available.plant has been selected for this study present study. The aim is to perform on anti-hyperlipidemic activity of ethanolic extract of leaves of Amaranthus tristis Linn against Triton wr-1339 induced hyperlipidemia in rats. Amaranthus tristis Linn administered a dose of 200mg/kg (p.o) to the triton induced hyperlipidemic rats. Amaranthus tristis Linn shows a significant decrease in the levels of serum cholesterol, phospholipids, triglyceride, LDL, VLDL and significant increase in the level of serum HDL level.Keywords
Amaranthus tristis Linn, Hyperlipidemia. LDL, VLDL, HDL.
- Evaluation of Diuretic Activity on Leaves Extract of Cardiospermum halicacabum Linn
Abstract Views :169 |
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, IN
2 PGP College of Pharmaceutical Science and Research Institute, Namakkal, Tamilnadu, IN
1 Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, IN
2 PGP College of Pharmaceutical Science and Research Institute, Namakkal, Tamilnadu, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 4 (2019), Pagination: 1607-1609Abstract
In this work we studied the diuretic potential of aqueous and ethanolic leaves extract of Cardiospermum halicacabum Linn in experimental Wister rats. The ethanolic extract was done by Continuous Hot Percolation method and the aqueous extract was done by Maceration method. Both aqueous and ethanolic Extract of Cardiospermum halicacabum Linn was tested to check the presence of different active constituents like alkaloids, flavonoids, glycosides, terpenoids and saponins. The aqueous and ethanolic leaves extract Cardiospermum halicacabum Linn was used for diuretic activity at the dose 200 mg/kg was compared with standard drug furosemide (10 mg/kg). Various ion concentrations like Sodium, Potassium, Chloride and urine volume was measured. Urine volume increases in aqueous extract than the ethanolic extract. Both the extract showed more urine volume when compared to control but less than that of standard drug. The significant increases in Sodium, Potassium and Chloride ion concentration in both the extract group.Keywords
Cardiospermum halicacabum Linn, Continuous Hot Percolation, Diuretic activity, Furosemide.References
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